An interesting new study just out looks at why people without the usual coeliac markers (like gliadin and transglutaminase antibodies) do in fact react to wheat and grains.
(By the way, I’m not even going to go into the fact that they are only looking for limited markers so miss most of them anyway, unlike the improved Cyrex 3 option; still not 100%, but FAR better.)
I know this doesn’t sound like news to us as we’ve been talking about the fact that non-coeliac gluten sensitivity involves a weakening of the gut barrier strength and allows systemic immune response for ages (see the Barrier Plan I wrote in 2011, for example, now the Gluten Plan!).
That said: it is always good to have a study confirm it for us – it makes it more likely to be accepted in mainstream medicine, and helps show us we are not going mad – even if docs couldn’t ‘see’ it before and told us we were imagining it. (Don’t set me off..).
Anyway, you can read the new study below. Effectively – markers for leaky gut found and systemic immune response leading to a reason why people consuming wheat and similar grains (not sure which they tested specifically) have ‘reactions’ even though they are not coeliac.
Weakened intestinal barrier, systemic immune activation may explain symptoms in people without celiac disease
It’s all very well finding the markers and confirming the leaky gut and immune activity, but exactly what do you do about it? The Gluten Plan has my full protocol in it for you, of course. Also, see here for my leaky gut factsheet.
In fact, just this morning, I was reading another study done locally (to me) in Plymouth where they have been investigating the cause and treatment of leaky gut which is so prevalent in athletes apparently (new one on me!).
They determined that heavy exercise and increased temperature (from the exercise raising body temperature and actual heat the athletes train in) causes the barrier to become more permeable. And they found that zinc carnosine combined with colostrum is an excellent way to prevent and treat it.
Yes, of course zinc carnosine is one of the leaky gut protocol choices in the Gluten Plan, I thank you. However, I wouldn’t recommend a dairy based colostrum product for a TGF leaky gut since we know it is a very common gluten cross-reactive food. Check the plan for different choices to suit different issues.
Anyway, good research proving what we already know = progress.