Diabetes and Metabolic Syndrome Tests

HOW TO ORDER LAB TESTS….

You can view details, sample reports, collection instructions and order all tests mentioned via Regenerus (RG), Medichecks (MC), via me (PHC) and Cyrex (Cyrex).

Use the search facility at each lab to find the test I’ve mentioned. Please direct all questions on doing tests, shipping, payment, getting results, interpretation etc to the labs. For Cyrex and PHC tests, you can contact me after reading the FAQ and tips on each page if you’re still stuck. You should get your results within 3 weeks (working days) direct from the labs (or me for PHC/Cyrex). Medichecks includes phlebotomy, Regenerus has a list of phlebotomy clinics where you can get blood samples taken.

For interpretation, please see the videos I am gradually adding to each page, or the You Tube channel here. There are also factsheets available here as I write them.

Unsure if you need a Diabetes/Metabolic Syndrome Test?

Diabetes Type 2 is so avoidable and reversible, it hurts my heart to see so many people develop complications with it and be on life-long medicine.

Prediabetes and Metabolic Syndrome

Pre-diabetes or ‘impaired glucose tolerance’ is usually the first step in insulin resistance and it is relatively easy to find. Many people with pre-diabetes will go on to develop full-blown Type 2 despite the fact that, in most cases, diabetes can be completely avoided through dietary and lifestyle changes.

Pre-diabetes is a risk factor for heart disease and metabolic syndrome. Metabolic syndrome is an umbrella term for several factors that come together, and people who fit the criteria for it have a significantly higher risk of heart disease and Type 2 diabetes. The criteria usually includes:

Excess abdominal fat or body mass index (BMI) >30

High triglycerides or need for cholesterol medication

Low HDL cholesterol or need for cholesterol medication

Hypertension (high blood pressure) or need for hypertension medication

Fasting glucose > 100 mg/dL

Family or personal history of cardiovascular disease, high cholesterol or type 2 diabetes

Personal history of chronic inflammatory disease

Contributing factors may include obesity, insulin resistance, polycystic ovary disease, hormone imbalance or a sedentary, unhealthy (smoking, etc.) lifestyle.   Poor dietary choices (highly processed, high fat, high salt, high sugar ’empty-calorie’ foods), combined with sedentary habits interact with our genetic programming: we store extra calories as fat. 

Fat cells (adipocytes) produce hormones (adipokines) that interact with the hypothalamus and or immune system and may have pro-inflammatory or anti-inflammatory effects.  Altered adipokine levels have been observed in Metabolic Syndrome and insulin resistance is a hallmark of it.

So, wouldn’t it be useful to know if that describes you – loooong before any diabetes actually develops? Yup. It would.

Testing Summary

Do the DD Metabolomic Profile (serum) (RG) for metabolic syndrome and blood sugar control markers. Or, include cardio and lipid scores too with the CardioMetabolic Profile (serum) (RG). Choose simpler progress/checker tests as below if needed.

The Belly Fat Plan

Belly Fat Plan cover

This Belly Fat Plan is based on what worked in-clinic for stubborn weight loss patients, as well as those who had constant water retention and/or bloating. People vastly under-estimate the effect food sensitivity, especially to the common gluten and dairy, can have on weight and the ability to shift it.

On top of that, most people who hold fat around their bellies are not balancing their insulin very well. To put that right and stop producing so much of the so-called ‘fat hormone,’ you need to follow a higher protein, lower carb diet. This used to be a low GI (glycaemic index) diet, but is now much more about the total load of the diet rather than each individual food, hence GL (glycaemic load).

The book includes a quick reference guide on the best and worst GL foods, a quick start plan, a larder list, loads of recipe and meal ideas and much more.

Trust me, if your scores are higher than they should be, or you fall into some of the risk categories, just changing this one thing will probably solve it. Just do it!

Pre-diabetes markers

Here is a rundown from the lab of what tests like these look for – they are a world away from normal mainstream tests. These are the pre-diabetes markers:

Haemoglobin A1c (HbA1c) – estimates the average blood glucose concentration for the life of the red blood cell (120 days).

Glycomark (1,5-anhydroglucitol) – more specific than the usual HbA1c, this shows likely blood sugar spikes after meals during the last 2 weeks rather than over 4 months. ‘Postprandial hyperglycaemia,’ as it is termed, is associated with cardiovascular disease and the reduction of hyperglycaemic events appear to decrease macro- and microvascular complications in diabetic patients. Low 1,5-AG is also associated with renal damage. 

Insulin – levels of insulin rise early in type 2 diabetes and then decrease as pancreatic beta cells lose function.

Leptin – is a hormone produced by adipocytes to provide a satiety ‘full’ signal to the hypothalamus. Elevated circulating levels of leptin are associated with high body fat and leptin resistance. High levels of this adipokine have pro-inflammatory effects and leptin accelerates arterial foam cell formation. 

Adiponectin – improves insulin sensitivity and stimulates glucose uptake and hepatic fatty acid oxidation. Very low levels of this anti-inflammatory adipokine may increase the risk of heart disease and some cancers.


Leptin to Adiponectin ratio– the ratio of leptin to adiponectin appears to be a sensitive indicator for a variety of adverse health conditions.


Cystatin C, Creatinine and eGFR  – renal damage is a common consequence of Metabolic Syndrome and hyperglycaemia.

It’s essentially an early warning test and I wish more people would do it!

Simpler/Progress Markers

You can also do some of the tests separately. Use Insulin Fasting (RG), Insulin Resistance Blood Test (MC) or the Diabetes Check Plus Test (MC), which includes glucose and HbA1c. All of those would be great progress tests, but the full Metabolomic Profile Serum (RG) is always going to be best.

HOW TO ORDER LAB TESTS….

You can view details, sample reports, collection instructions and order all tests mentioned via Regenerus (RG), Medichecks (MC), via me (PHC) and Cyrex (Cyrex).

Use the search facility at each lab to find the test I’ve mentioned. Please direct all questions on doing tests, shipping, payment, getting results, interpretation etc to the labs. For Cyrex and PHC tests, you can contact me after reading the FAQ and tips on each page if you’re still stuck. You should get your results within 3 weeks (working days) direct from the labs (or me for PHC/Cyrex). Medichecks includes phlebotomy, Regenerus has a list of phlebotomy clinics where you can get blood samples taken.

For interpretation, please see the videos I am gradually adding to each page, or the You Tube channel here. There are also factsheets available here as I write them.

Testing Summary

Do the DD Metabolomic Profile (serum) (RG) for metabolic syndrome and blood sugar control markers. Or, include cardio and lipid scores too with the CardioMetabolic Profile (serum) (RG). Choose simpler progress/checker tests as above if needed.