Covid and the Brain: Neuroinflammation? Blood Brain Barrier?

I think I said right at the start of this in my Covid factsheet that I would be tempted to make sure there was no blood brain barrier (BBB) breach or neuroinflammation (NI) ongoing after Covid infections. I was worried that some people were having hallucinations etc. Ongoing NI can cause all sorts of problems later down the line.

Today, this comes out – Covid is definitely affecting the brain. It may be nothing to do with NI, but if it were me, I’d be looking to check the BBB was OK – viruses are known to affect it – and to bring down any NI. Check my Brain factsheet for more info – halfway down, there’s a list of typical NI symptoms. To check the BBB, you would use a Cyrex 20.

Sharing in case, anyway.

Neurological and Psychiatric Effects of COVID

Around 1 in 3 COVID-19 survivors developed a mental health condition within 6 months of infection with the SARS-CoV-2 virus, an observational study has found.

The research, published in The Lancet Psychiatry journal, estimated that 33.6% of people who recovered from COVID went on to receive a neurological or psychiatric diagnosis within the time frame.

Among the most common conditions, anxiety rates were estimated as affecting 17%, and mood disorders, 14%.

Neurological diagnoses such as stroke and dementia were rarer but not uncommon, the research team led by the University of Oxford reported.

Prof Paul Harrison, who led the study, said: “Although the individual risks for most disorders are small, the effect across the whole population may be substantial for health and social care systems due to the scale of the pandemic and that many of these conditions are chronic.

The study was based on electronic health records of 236,379 COVID-19 patients, mostly from the US.

Commenting on the findings for the Science Media Centre, Prof Sir Simon Wessely, regius chair of psychiatry at King’s College London, said: “It confirms beyond any reasonable doubt that COVID-19 affects both brain and mind in equal measure.”

Dr Musa Sami, clinical associate professor in psychiatry at the University of Nottingham, said: “This data provides very important information for services and policy makers to estimate the burden of neurological and psychiatric disease from COVID-19.”

Source: Medscape

Hmm…..forewarned is forearmed.

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