I am coming across quite a few people who, despite supplementation and the usual approaches, just can’t seem to get their Vitamin D level up to what I would term adequate levels. See my Vitamin D factsheet here for more on specifics.
So, I was interested to see a paper here in Orthomolecular News discussing genetic and acquired Vitamin D resistance. Do have a read if you’re having issues with Vitamin D, but here’s a bit to start you off:
Vitamin D resistance is a complex condition that can arise from a combination of genetic, physiological, and lifestyle factors. These factors include poor dietary habits (such as diets high in carbohydrates, seed oils rich in omega-6 fats, and ultra-processed foods), inadequate sleep, lack of exercise and sun exposure, certain prescription medications, exposure to heavy metals and chemical toxins, vitamin and micronutrient deficiencies, hormonal imbalances, and chronic infections. Understanding and addressing these interconnected factors is essential for overcoming vitamin D resistance and ensuring optimal vitamin D status for health.
Orthomolecular News
I was particularly fascinated by the link between Vitamin D resistance and chronic infections, the thyroid and oestrogen, progesterone and testosterone levels. Who knew? Ruddy hormones again! We are all so internally inter-connected, aren’t we?!
Anyway, quite a long piece, and I’m not sure I agree with their recommendation of methylene blue myself?? Have you come across that?
Hope it helps x